Journal: American Journal of Translational Research
Article Title: Dendritic cells modified by tumor associated antigen SMP30 have enhanced antitumor effect against mouse hepatocarcinoma cells in vitro and in vivo
doi:
Figure Lengend Snippet: Construction of BALB/c nude mouse models of subcutaneous xenografts. A. BALB/c nude mice with equal-sized (~100 mm3) single H22 tumors were treated with CD3+CD8+ T cells. B. Recording chart of tumor growth process. C. Tumor volume on day 15: PBS group, Untreated group, LV group, Protein group, LV-SMP30 group (from left to right). D. Tumors harvested from mice on day 15: PBS group, Untreated group, LV group, Protein group, LV-SMP30 group (from left to right). E. Tumor growth curve. These results demonstrated that the tumor volume in the LV-SMP30 group was smaller than that of other control groups (P<0.05).
Article Snippet: Mouse liver cancer cell lines H22 and Hep1-6 were employed, purchased from iCell Bioscience Inc.
Techniques: Control